Fig. 1: FGF14-AS2 is significantly downregulated in breast cancer and correlated with breast cancer progression. | Cell Death Discovery

Fig. 1: FGF14-AS2 is significantly downregulated in breast cancer and correlated with breast cancer progression.

From: Long noncoding RNA FGF14-AS2 inhibits breast cancer metastasis by regulating the miR-370-3p/FGF14 axis

Fig. 1

a Hierarchical clustering analysis of differentially expressed lncRNAs in breast cancer tissues (Tumor) and non-tumorous samples (Normal) from the GSE29431 dataset (fold change >2; P < 0.05). b Relative expression of FGF14-AS2 in breast cancer tissues (Tumor) compared with non-tumor samples (Normal) in the GSE29431 dataset. c Relative expression of FGF14-AS2 in breast cancer tissues (Tumor) compared with non-tumorous samples (Normal) in the GSE54002 dataset. d qRT-PCR determination of relative expression levels of FGF14-AS2 in 45 pairs of breast cancer tissues and corresponding adjacent non-cancerous tissues. e qRT-PCR detection of the relative expression levels of FGF14-AS2 in normal breast epithelial cell line (HBL-100) and breast cancer cell lines (MCF-7, MDA-MB-453, MDA-MB-231, and HCC-1937). f Relative expression levels of FGF14-AS2 in patients with early-stage (I/II) and advanced-stage (III/IV) breast cancer. Data are the mean ± SD of three independent experiments. **P < 0.01; ****P < 0.0001.

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