Fig. 5: Astrocyte hepcidin overexpression prevented Aβ-induced dysregulation of iron homeostasis. | Cell Death Discovery

Fig. 5: Astrocyte hepcidin overexpression prevented Aβ-induced dysregulation of iron homeostasis.

From: Hepcidin overexpression in astrocytes alters brain iron metabolism and protects against amyloid-β induced brain damage in mice

Fig. 5: Astrocyte hepcidin overexpression prevented Aβ-induced dysregulation of iron homeostasis.

Western blot was used to detect expression levels of FPN1, TfR1, and DMT1( + IRE) in the cortex (a–d) and hippocampus (e–h) of mice in different groups. Their relative expression levels in different groups as compared to the control group were calculated after normalizing each specific band to its respective β-actin band, and are presented as means ± SEM, n = 6. *P < 0.05 and **P < 0.01.

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