Fig. 1: Physiological localization of the NF-κB p65-subunit in the pancreas of (A) newborn (P1), (B) neonate (P12), and (C) young adult (4 weeks) NOD/ToIβ mice.

Pancreata of untreated (control) or Dox-treated during the embryonic period (E11–P1) or for 3 weeks after birth (P1–P21) were immunostained for p65 (red), insulin (green), and DNA (blue). Pictures are representative confocal images of islets from three to five different mice per group. For each mouse, ~15 islets were analyzed. Original images were taken at a magnification of ×40. Inset images were digitally increased ×4.