Fig. 1: Acute kidney injury induced by renal ischemia and reperfusion. | Cell Death Discovery

Fig. 1: Acute kidney injury induced by renal ischemia and reperfusion.

From: LncRNA GAS5 promotes apoptosis as a competing endogenous RNA for miR-21 via thrombospondin 1 in ischemic AKI

Fig. 1

The levels of serum creatinine (a), miR-21 (b), GAS5 (c), TSP-1 mRNA (d), and TSP-1 protein (f) in mice subjected to renal ischemia for 35 min, followed by various reperfusion time. e Representative image of ISH for miR-21 and TSP-1 (photographed at ×20 magnification). g Histopathological changes (×20 magnification) and apoptosis in mice kidneys induced by renal ischemia and reperfusion (×40 magnification) evaluated by the TUNEL method. N = 4, *P < 0.05, **P < 0.01 vs. the Sham group. Scale bars, 100 μm.

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