Fig. 5: Synergistic inhibition of IKKβ/NF-κB and ETS by combination of Dasatinib with IKKβ inhibitor, CmpdA. | Cell Death Discovery

Fig. 5: Synergistic inhibition of IKKβ/NF-κB and ETS by combination of Dasatinib with IKKβ inhibitor, CmpdA.

From: Inhibition of IKKβ/NF-κB signaling pathway to improve Dasatinib efficacy in suppression of cisplatin-resistant head and neck squamous cell carcinoma

Fig. 5

Cal27CP (a) and SCC25CP (b) cells were treated with vehicle control, CmpdA, Dasatinib, or a combination for 24 h, lysed, and phosphorylation and total levels of SRC and p65 and expression of ETS-1, cleaved-caspase-3, and β-actin were detected by Western blot analysis.

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