Fig. 2: Specific ablation of Rictor in tubular cells aggravates LPS-induced acute kidney injury in mice.

a The graph showing the blood urea nitrogen (BUN) levels in CDH16+-Rictor+/+ and CDH16+-Rictor−/− mice at day 1 after treated with LPS. Each vertical bar represents the mean ± SEM (n = 8) analyzed by students t test. *P < 0.05 vs. CDH16+-Rictor+/+ mice treated with LPS. c Kidney histology as shown by PAS staining. Scale bar = 20 μm. b The graph showing the injury scores among groups. Each vertical bar represents the mean ± SEM (n = 6) analyzed by one-way analysis of variance (ANOVA) followed by post hoc comparisons by Student–Newman–Keuls test. *p < 0.05 compared between different groups.