Table 3 Significant changing transcription factors in DCA-treated GES-1 cell line.
From: TGR5-HNF4α axis contributes to bile acid-induced gastric intestinal metaplasia markers expression
Gene symbol | Fold | Description |
|---|---|---|
ATF3 | 6.27 | Activating transcription factor 3 |
ATF4 | 4.73 | Activating transcription factor 4 |
CEBPA | 4.7 | CCAAT enhancer binding protein-α |
CEBPB | 5.07 | CCAAT enhancer binding protein-β |
CEBPG | 5.99 | CCAAT enhancer binding protein-γ |
E2F1 | 2.54 | E2F transcription factor 1 |
E2F6 | 2.69 | E2F transcription factor 6 |
EGR1 | 5.49 | Early growth response 1 |
ELK1 | 2.06 | ETS transcription factor ELK1 |
ESR1 | 2.42 | Estrogen receptor 1 |
FOS | 3.31 | Fos proto-oncogene |
FOXA2 | 2.42 | Forkhead box A2 |
FOXG1 | 2.42 | Forkhead box G1 |
GATA1 | 2.42 | GATA-binding protein 1 |
GATA3 | 2.42 | GATA-binding protein 3 |
GTF2B | 2.19 | General transcription factor IIB |
HAND1 | 2.42 | Heart and neural crest derivatives expressed 1 |
HNF1A | 2.42 | HNF1 homeobox A |
HNF4A | 2.53 | Hepatocyte nuclear factor 4α |
HSF1 | 2.53 | Heat shock transcription factor 1 |
IRF1 | 3.71 | Interferon regulatory factor 1 |
JUNB | 2.19 | JunB proto-oncogene |
MAX | 2.34 | MYC-associated factor X |
MEF2A | 3.08 | Myocyte enhancer factor 2A |
MEF2C | 2.42 | Myocyte enhancer factor 2C |
MYC | 3.74 | MYC proto-oncogene, bHLH transcription factor |
MYF5 | 2.42 | Myogenic factor 5 |
MYOD1 | 2.42 | Myogenic differentiation 1 |
NFATC2 | 2.42 | Nuclear factor of activated T cells 2 |
NFKB1 | 2.4 | Nuclear factor-κB subunit 1 |
PAX6 | 2.42 | Paired box 6 |
POU2AF1 | 2.42 | POU class 2 homeobox associating factor 1 |
PPARA | 2.66 | Peroxisome proliferator activated receptor-α |
PPARG | 3.59 | Peroxisome proliferator activated receptor-γ |
RELB | 9.33 | RELB proto-oncogene, NF-kB subunit |
SMAD1 | 17.72 | SMAD family member 1 |
STAT1 | 12.53 | Signal transducer and activator of transcription 1 |
STAT2 | 4.78 | Signal transducer and activator of transcription 2 |
TP53 | 3.13 | Tumor protein p53 |
B2M | 2.37 | β-2-Microglobulin |
ID1 | −6.67 | Inhibitor of DNA binding 1, HLH protein |
SMAD9 | −2.41 | SMAD family member 9 |
TFAP2A | −2.48 | Transcription factor AP-2α |
ACTB | −4.34 | Actin-β |
