Fig. 3: WHSC1 ablation promotes CRC cell apoptosis. | Cell Death Discovery

Fig. 3: WHSC1 ablation promotes CRC cell apoptosis.

From: Histone methyltransferase WHSC1 inhibits colorectal cancer cell apoptosis via targeting anti-apoptotic BCL2

Fig. 3: WHSC1 ablation promotes CRC cell apoptosis.The alternative text for this image may have been generated using AI.

a Profiling of the cell cycle distribution of HCT116 and DLD1 cells transiently expressing shCon, shWHSC1-1, or shWHSC1-2. b Quantitative analyses of the cell cycle distribution as described in (a), assessed by two-sided Student’s t test. c, d Flow cytometry profiling and quantification of Annexin-V/7-AAD-stained cells transiently expressing shCon, shWHSC1-1, or shWHSC-2. All data represent the mean ± S.D. of three independent experiments, *P < 0.05, **P < 0.01.

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