Fig. 1: The expression of SIRT4 was downregulated in HBV-related HCC tissues.

A qPCR analysis on mRNA expression of SIRT4 in 9 normal liver biopsies and 30 pairs of HCC tumor and their adjacent non-tumor tissues. B SIRT4 protein expression was slightly increased in HCC tumors than their adjacent non-tumor counterparts. Statistically significant differences are denoted by asterisks above the bars, ***p < 0.0001, *p < 0.01.