Fig. 5: Schematic illustration of the mechanisms that tumor-derived Igs enhanced tumor cell migration, invasion, and metastasis.
From: Current insights into the expression and functions of tumor-derived immunoglobulins
Tumor-derived Igs augmented multiple tumor cell migration, invasion, and metastasis through positively or negatively regulating the following cell signaling pathways or biological processes or important molecules, including SOX2 signaling pathway, FAK signaling pathway, EMT, differentiation, IL-1β, and E-cadherin.
