Fig. 4: K. pneumoniae activates microglia mediated inflammatory response in mice.

A, B Representative images and the quantification of IL-1β expression in the cortex and hippocaumps after PTZ injection. Compared with that in the controls, IL-1β expression was increased in the cortex and hippocampus in the K. pneumoniae group (n = 3 in each group; *P < 0.05, Student’s t test). C, D Representative images and the quantification of IL-6 expression in the cortex and hippocaumps after PTZ injection. Compared with that in the controls, IL-6 expression was increased in the cortex and hippocampus in the K. pneumoniae group (n = 3 in each group; *P < 0.05, Student’s t test).