Table 1 Statistical analysis of early phase GSTA2 protein with clinical and experimental variables of HCC recipients.

From: Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism

Variables

Early phase GSTA2

P value

Pretransplantation

Sex

 Male (N = 88)

486.6 (183.9–718.4)

0.160

 Female (N = 18)

436.7 (160.9–941.1)

 

Age

 ≤57

484.3 (230.0 – 941.1)

0.493

 >57

478.5 (160.9 – 667.8)

 

HbsAg before LT

 Positive (N = 85)

486.3 (160.9–941.1)

0.252

 Negative (N = 21)

455.6 (230.0–667.8)

 

Milan criteria

 Within (N = 59)

477.8 (160.9–718.4)

0.233

 Beyond (N = 47)

496.9 (183.9–941.1)

 

UCSF criteria

 Within (N = 74)

470.2 (160.9–718.4)

0.173

 Beyond (N = 32)

499.1 (183.9–941.1)

 

AFP level before LT

 ≤400 ng/ml (N = 89)

477.0 (160.9–941.1)

0.615

 >400 ng/ml (N = 17)

496.9 (242.0–632.2)

 

Type of graft

 Live graft (N = 81)

477.0 (160.9–718.4)

0.529

 Cadaveric graft (N = 25)

501.4 (256.5–941.1)

 

 Graft weight to recipient ESLV (%)

R = 0.113

0.248

 Pre–LT AST (μ/l, N = 106)

R = 0.127

0.195

 Pre-LT ALT (μ/l, N = 106)

R = 0.067

0.495

During and post-transplantation

  

Cold ischemic time (min) (N = 106)

R = 0.182

0.062

Warm ischemic time (min (N = 104)

R = 0.218

0.026*

Post-LT ROS level (N = 69)

R = 0.578

0.000***

Post –LT AST (μ/l, N = 106)

R = 0.268

0.022*

Post-LT ALT (μ/l, N = 106)

R = 0.300

0.031*

Post-LT bilirubin (mg/dl, N = 72)

R = 0.037

0.758

Post-LT-2 h GM-CSF (N = 100)

R = -0.108

0.283

Post-LT-2 h IFN-alpha2 (N = 100)

R = 0.060

0.550

Post-LT-2 h IFN-gamma (N = 100)

R = 0.030

0.768

Post-LT-2 h IL-10 (N = 100)

R = 0.359

0.000***

Post-LT-2 h IL-6 (N = 100)

R = 0.052

0.606

Post-LT-2 h IL-8 (N = 100)

R = 0.306

0.002**

Post-LT-2 h IP-10 (N = 100)

R = 0.120

0.234

Post-LT-2 h MCP-1 (N = 100)

R = 0.105

0.297

Post-LT-2 h TNF-alpha (N = 100)

R = 0.026

0.795

  1. *P < 0.05.
  2. **P < 0.01.
  3. ***P < 0.001.