Fig. 1: FBW7 is under-expressed in the T1D mouse model. | Cell Death Discovery

Fig. 1: FBW7 is under-expressed in the T1D mouse model.

From: Suppressive role of E3 ubiquitin ligase FBW7 in type I diabetes in non-obese diabetic mice through mediation of ubiquitination of EZH2

Fig. 1

A The blood glucose level in the mouse model. B Western blot results of FBW7 expression in islets from T1D mice (n = 10) and control mice (n = 10), *p < 0.05, vs. the normal group. C Representative images of IHC for FBW7 expression in islets from T1D mice and control mice with arrows pointing at cells positive for FBW7 (bar = 25 μm). Measurement data are presented. Data comparisons between two groups were analyzed by unpaired t-test. Statistical analysis in relation to time-based measurements within each group was realized using repeated-measures ANOVA.

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