Fig. 2: Ci promotes Hid-induced apoptosis.
From: The Hh pathway promotes cell apoptosis through Ci-Rdx-Diap1 axis
All eye imaginal disks shown in this figure were oriented with anterior on the left. a A control eye disc was stained with PH3 antibody to mark proliferative cells. b Knockdown of ci did not affect PH3 signals under GMR-hid background. c Overexpression of ci did not regulate cell proliferation. d Quantification analyses the PH3-positive cells of a–c (n ≥ 6). e A control eye disc was stained to show Ci (green) and Cas3 (white). f Knockdown of ci decreased apoptosis. g Overexpression of ci promoted apoptosis. h Quantification analyses the Cas3-positive cells of e–g (n ≥ 6). Scale bars: 50 μm for all eye disks.
