Fig. 1: COL5A1 mRNA expression in various subtypes of glioma and its correlations with several events. | Cell Death Discovery

Fig. 1: COL5A1 mRNA expression in various subtypes of glioma and its correlations with several events.

From: Type V collagen alpha 1 chain promotes the malignancy of glioblastoma through PPRC1-ESM1 axis activation and extracellular matrix remodeling

Fig. 1

A The heatmap shows the correlation between the mRNA expression levels of various collagen family members in neural/GBM tissues from Oncomine (Lee brain cohort, n = 25). B The heatmap shows the correlation between the mRNA expression level of collagen V family members in normal brain/GBM tissues from Oncomine (Murata brain cohort, n = 84). C The heatmap shows the endogenous mRNA expression levels of several targets, genetic alteration events, and subtypes in the TCGA-specific template (copy number for EGFR, PTEN, and chromosomes 1, 7, 10, and 19 in TCGA brain tumors, n = 1119). D Kaplan–Meier curves of overall survival in glioblastoma patients with or without TMZ treatment and radiotherapy based on a high or low COL5A1 mRNA expression level (p = 9.8e−4, p = 5.4e−4 and p = 4.9e−4, respectively). The significance of the differences in (D) was analyzed using Student’s t test.

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