Table 2 Multivariate analysis of COL5A1 expression and clinical parameters in gliomas.

From: Type V collagen alpha 1 chain promotes the malignancy of glioblastoma through PPRC1-ESM1 axis activation and extracellular matrix remodeling

 

Multivariate analysis

Variable

Hazard ratio

95% confidence interval

p value

Sex (male/female)

2.147

0.958–4.812

0.064

Age (<65/65)

8.168

1.923–34.698

0.004*

IDH1 R132H (negative/positive)

1.202

0.699–2.066

0.506

ATRX (preserved/lost)

1.203

0.507–2.853

0.675

H3 K27M (negative/positive)

0.979

0.597–1.606

0.933

MGMT (preserved/lost)

0.555

0.252–1.221

0.143

EGFR (negative/positive)

0.637

0.195–2.081

0.455

EGFRvIII (negative/positive)

0.877

0.531–1.447

0.607

P53 (negative/overexpressed)

1.438

1.065–2.142

0.024*

Neurofilament (negative/positive)

2.054

1.015–4.153

0.045*

NF1 (negative/positive)

0.693

0.419–1.147

0.154

PDGFRA (negative/positive)

2.285

1.005–5.194

0.049*

COL5A1(negative/positive)

1.260

1.522–3.038

0.047*

  1. *A p value < 0.05 was considered significant.