Table 1 Clinicopathological characteristics of ccRCC patients in relation to KDM4D expression level.

From: Histone demethylase KDM4D inhibition suppresses renal cancer progression and angiogenesis through JAG1 signaling

Characteristics

Patients

Tumor KDM4D expression

p-value

n

%

Low

High

All patients

70

100

43

27

Ā 

Gender

Ā Ā Ā Ā 

0.899

Male

55

78.6%

34

21

Ā 

Female

15

21.4%

9

6

Ā 

Age (years)

Ā Ā Ā Ā 

0.508

≤55

32

45.7%

21

11

Ā 

>55

38

54.3%

22

16

Ā 

TNM stage

Ā Ā Ā Ā 

0.256

I+II

68

97.1%

41

27

Ā 

III+IV

2

2.9%

2

0

Ā 

pT stage

Ā Ā Ā Ā 

0.256

T1 + T2

68

97.1%

41

27

Ā 

T3 + T4

2

2.9%

2

0

Ā 

pN stage

Ā Ā Ā Ā 

0

N0

70

100%

43

27

Ā 

N1

0

0

0

0

Ā 

Pm stage

Ā Ā Ā Ā 

0

M0

70

100%

43

27

Ā 

M1

0

0

0

0

Ā 

Furman grade

Ā Ā Ā Ā 

0.0118*

I + II

57

81.4%

39

18

Ā 

III + IV

13

18.6%

4

9

Ā 

Tumor size(cm)

Ā Ā Ā Ā 

0.606

≤4

39

55.7%

25

14

Ā 

>5

31

44.3%

18

13

Ā 

Metastasis for surgery

Ā Ā Ā Ā 

0.00475*

Yes

16

11.4%

5

11

Ā 

No

54

88.6%

38

16

Ā