Fig. 1: The effects of cell death inhibitors on myocardial infarct size and hippocampal dendritic spine density.
From: Cell death inhibitors protect against brain damage caused by cardiac ischemia/reperfusion injury
A Representative images of heart slices using Evans blue-TTC staining (upper panel) and quantitative evaluation of myocardial infarct size/AAR (lower panel, n = 6/group); B representative images of dendritic spine density (upper panel) and the number of dendritic spines per 10 μm dendrites at hippocampal CA1 region (lower panel, n = 8–12/group, 2–3 slides/sample). Data are shown as mean ± SEM. *P < 0.05 vs. Sham, †P < 0.05 vs. Cardiac I/R + Vehicle, ‡P < 0.05 vs. medium dose of Z-VAD. Veh: cardiac I/R rats treated with vehicle; L: cardiac I/R rats treated with low dose of cell death inhibitor; M: cardiac I/R rats treated with medium dose of cell death inhibitor; H: cardiac I/R rats treated with high dose of cell death inhibitor. AAR area at risk, I/R ischemia/reperfusion injury.
