Table 2 Univariate and multivariate Cox analysis of cohort-2 (training cohort) for overall survival.

From: RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner

Factors

Univariate analysis

Multivariate analysis

HR

95% CI

p

HR

95% CI

p

Gender

 Female

1

 

0.175

   

 Male

0.77

0.52–1.13

    

Age

 ≤73

1

 

0.051

1

 

0.043

 >73

1.62

1.00–2.64

 

1.49

1.01–2.21

 

Histologic grade

 G1

1

 

0.686

   

 G2

1.21

0.66–2.21

    

 G3

1.21

0.64–2.28

    

 G4

1.91

0.68–5.38

    

TNM stage

      

 I stage

1

 

0.000

1

 

0.000

 II stage

1.49

0.89–2.50

 

1.33

0.79–2.24

 

 III stage

3.06

1.98–4.73

 

2.95

1.90–4.56

 

 IV stage

6.44

1.97–20.99

 

7.84

2.38–25.86

 

Family history of HCC

 No

1

 

0.617

   

 Yes

1.11

0.74–1.67

    

RBM15

 Low

1

 

0.044

1

 

0.043

 High

1.47

1.01–2.15

2.15

1.49

1.01–2.21

 
  1. HR hazard ratio, CI confidence interval.
  2. p value was measured by Cox proportional hazard regressions.
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