Fig. 6: RvD1 promotes apoptosis of BMDMs through Fas. | Cell Death Discovery

Fig. 6: RvD1 promotes apoptosis of BMDMs through Fas.

From: RvD1 accelerates the resolution of inflammation by promoting apoptosis of the recruited macrophages via the ALX/FasL-FasR/caspase-3 signaling pathway

Fig. 6

A RvD1 promotes LPS-induced apoptosis in BMDMs. B Caspase 8 activity was also measured in BMDMs. Expression of cleaved caspase-3 (C) and cleaved PARP (D) was measured using western blotting. mRNA expression of Fas (E), Mcl-1 (F), and Bax (G) was measured using qPCR. H Western blot was used to confirm that RvD1 has no effect on Bax/Bcl-2.

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