Fig. 2: HMGA1 promotes the proliferation and invasion of CCA cells.
From: Overexpression of HMGA1 confers radioresistance by transactivating RAD51 in cholangiocarcinoma
A, B The effect of HMGA1 on the proliferation of CCA cells was examined by clonogenic (A) and EdU (B) assays of CCA cells with HMGA1 overexpression or knockdown (n = 3 biologically independent samples). C Matrigel invasion data showing that overexpression of HMGA1 significantly enhanced the invasion capacity, whereas knockdown of HMGA1 decreased the invasion potential of CCA cells (n = 3 biologically independent samples). The P-value was obtained by Student’s t test. The results represent the mean ± S.D. of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.
