Fig. 2: piR-57125 inhibits ccRCC metastasis.

a Transwell assay showed that knockdown of piR-57125 promoted 786-O and OSRC-2 cell metastasis. Data represent mean ± S.D. from three independent experiments. b Wound healing assay demonstrated that knockdown of piR-57125 enhance 786-O and OSRC-2 cells’ metastatic ability. Data represent mean ± S.D. from three independent experiments. c Transwell assay showed that the metastatic ability of ccRCC cells was inhibited when piR-57125 was overexpressed. Data represent mean ± S.D. from three independent experiments. d wound healing assay revealed that overexpression of piR-57125 slowed the metastatic rate of 786-O and OSRC-2 cells. Data represent mean ± S.D. from three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.