Fig. 2: CD5L deficiency inhibits the activation of JNK and ERK signaling pathways. | Cell Death Discovery

Fig. 2: CD5L deficiency inhibits the activation of JNK and ERK signaling pathways.

From: CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway

Fig. 2

A CYP-2E1 protein in the liver of each group was examined by Western blotting at specified time point after administration. A representative blot and the means ± SD of three independent analyses were shown; B, C Level of GSH and APAP-AD in liver at specified time point after administration. The levels of specific proteins in WT and CD5L−/− mouse liver were detected by western blotting after treatment with PBS or APAP for 0,1,3 h (D) and 24 h (E). The phosphorylated proteins were evaluated by western blotting analysis normalized to total proteins. A representative blot and the means ± SD of three independent analyses. *P < 0.05; **P < 0.01; ***P < 0.001.

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