Fig. 2: LncRNA SND1-IT1 knockdown inhibited GC cell proliferation and TGF-β1-induced EMT. | Cell Death Discovery

Fig. 2: LncRNA SND1-IT1 knockdown inhibited GC cell proliferation and TGF-β1-induced EMT.

From: LncRNA SND1-IT1 facilitates TGF-β1-induced epithelial-to-mesenchymal transition via miR-124/COL4A1 axis in gastric cancer

Fig. 2

A sh-SND1-IT1 was constructed in HGC-27 cells. Subsequent analyses were performed in untreated HGC-27 cells, HGC-27 cells expressing empty vector, and HGC-27 cells expressing lncRNA SND1-IT1. B HGC-27 cell viability was examined by CCK-8 assays. C Representative photomicrographs of HGC-27 cells migrating or invading from upper transwell chambers into bottom ones. D Quantitative analysis of HGC-27 cells migrating or invading from upper transwell chambers into bottom ones. E Representative immunoblots and quantitative analysis of E-cadherin, N-cadherin in HGC-27 cells. The results were normalized to the β-actin expression. Values are expressed as mean ± SD from three technical repeats. **P < 0.01.

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