Table 1 Clinical histopathological features of OSCC samples used for IHC staining, CAFs’ isolation, culture and transfection.
Factors | Subtypes | n1 (n1/N1) | n2 (n2/N2) | n3 (n3/N3) |
|---|---|---|---|---|
Gender | Male | 55 (64.7%) | 9 (60.0%) | 3 (50.0%) |
Female | 30 (35.3%) | 6 (40.0%) | 3 (50.0%) | |
Age (years) | ≤60 | 43 (50.6%) | 7 (46.7%) | 5 (83.3%) |
>60 | 42 (49.4%) | 8 (53.3%) | 1 (16.7%) | |
Location in the oral site | Tongue | 17 (20.0%) | 4 (26.7%) | 2 (33.3%) |
Buccal | 19 (22.4%) | 6 (40.0%) | 1 (16.7%) | |
Gingival | 7 (8.2%) | 2 (13.3%) | 1 (16.7%) | |
Floor of oral | 12 (14.1%) | 2 (13.3%) | 2 (33.3%) | |
Others | 30 (35.3%) | 1 (6.7%) | 0 (0.0%) | |
Differentiation | Well | 37 (43.5%) | 6 (40.0%) | 3 (50.0%) |
Mild | 23 (27.1%) | 5 (33.3%) | 2 (33.3%) | |
Poor | 25 (29.4%) | 4 (26.7%) | 1 (16.7%) | |
T stage (tumor volume) | T1 | 21 (24.7%) | 4 (26.7%) | 3 (50.0%) |
T2 | 34 (40.0%) | 6 (40%) | 2 (33.3%) | |
T3 | 18 (21.2%) | 1 (6.7%) | 0 (0.0%) | |
T4 | 12 (14.1%) | 4 (26.7%) | 1 (16.7%) | |
Lymph node metastasis | Negative | 46 (54.1%) | 8 (53.3%) | 3 (50.0%) |
Positive | 39 (45.9%) | 7 (46.7%) | 3 (50.0%) | |
Clinical stage | I/II | 57 (67.1%) | 7 (46.7%) | 3 (50.0%) |
III/IV | 28 (32.9%) | 8 (53.3%) | 3 (50.0%) |