Table 1 Clinical histopathological features of OSCC samples used for IHC staining, CAFs’ isolation, culture and transfection.

From: TGF-βRII regulates glucose metabolism in oral cancer-associated fibroblasts via promoting PKM2 nuclear translocation

Factors

Subtypes

n1 (n1/N1)

n2 (n2/N2)

n3 (n3/N3)

Gender

Male

55 (64.7%)

9 (60.0%)

3 (50.0%)

Female

30 (35.3%)

6 (40.0%)

3 (50.0%)

Age (years)

≤60

43 (50.6%)

7 (46.7%)

5 (83.3%)

>60

42 (49.4%)

8 (53.3%)

1 (16.7%)

Location in the oral site

Tongue

17 (20.0%)

4 (26.7%)

2 (33.3%)

Buccal

19 (22.4%)

6 (40.0%)

1 (16.7%)

Gingival

7 (8.2%)

2 (13.3%)

1 (16.7%)

Floor of oral

12 (14.1%)

2 (13.3%)

2 (33.3%)

Others

30 (35.3%)

1 (6.7%)

0 (0.0%)

Differentiation

Well

37 (43.5%)

6 (40.0%)

3 (50.0%)

Mild

23 (27.1%)

5 (33.3%)

2 (33.3%)

Poor

25 (29.4%)

4 (26.7%)

1 (16.7%)

T stage (tumor volume)

T1

21 (24.7%)

4 (26.7%)

3 (50.0%)

T2

34 (40.0%)

6 (40%)

2 (33.3%)

T3

18 (21.2%)

1 (6.7%)

0 (0.0%)

T4

12 (14.1%)

4 (26.7%)

1 (16.7%)

Lymph node metastasis

Negative

46 (54.1%)

8 (53.3%)

3 (50.0%)

Positive

39 (45.9%)

7 (46.7%)

3 (50.0%)

Clinical stage

I/II

57 (67.1%)

7 (46.7%)

3 (50.0%)

III/IV

28 (32.9%)

8 (53.3%)

3 (50.0%)

  1. N/T number in total cases, n1 number of OSCC tissues for IHC staining, N1 85 cases, n2 number of OSCC tissues for CAFs’ isolation and primary cell culture, N2 15 cases, n3 number of OSCC tissues for CAFs’ transfection in vitro, N3 6 cases.