Fig. 1: ZC3H15 was upregulated in GC and high expression of ZC3H15 was correlated with poor patient prognosis. | Cell Death Discovery

Fig. 1: ZC3H15 was upregulated in GC and high expression of ZC3H15 was correlated with poor patient prognosis.

From: ZC3H15 promotes gastric cancer progression by targeting the FBXW7/c-Myc pathway

Fig. 1

A Up-regulation of ZC3H15 was found in 8 of 20 cancer types. B, C The level of ZC3H15 mRNA was significantly increased from normal stomach tissues to gastric cancer tissues in DErrico and Cho dataset and P-values were indicated. D, E Kaplan–Meier analysis of overall survival using data from the GSE14210 and GSE15459 database and P-values were indicated. F Immunohistochemical analyses of ZC3H15 expression in eight paired samples of gastric cancer and normal stomach tissue, P < 0.001. The data were expressed as mean ± SD. Student’s t-test was performed to analyze significance. G Western blot analyses were used to examine ZC3H15 expression in GES-1 cells and gastric cancer cell lines.

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