Fig. 1: Identification of an m6A reader IGF2BP3 whose overexpression is associated with NPC prognosis. | Cell Death Discovery

Fig. 1: Identification of an m6A reader IGF2BP3 whose overexpression is associated with NPC prognosis.

From: MYC-activated RNA N6-methyladenosine reader IGF2BP3 promotes cell proliferation and metastasis in nasopharyngeal carcinoma

Fig. 1

a Bioinformation analysis showed the IGF2BP3 expression in normal nasopharyngeal tissues (n = 3) and the NPC tissues (n = 25) based on the GEO datasets (GSE13597). b, c The expression level of IGF2BP3 was detected by IHC analysis (c) and assessed by H-score (b) in normal tissues (n = 10) and NPC tissues (n = 70). d–f IGF2BP3 expression was analyzed in normal and NPC patients regarding tumor grade (d), N stage (e), and T stage (f), using H-score. g Kaplan–Meier analysis showed that the expression of IGF2BP3 was a predictive factor of overall survival in NPC. Data was shown as the mean ± standard deviation of three independent experiments. *P < 0.05, **P < 0.01.

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