Fig. 2: DEG analysis and identification of ECM1 as the target gene. | Cell Death Discovery

Fig. 2: DEG analysis and identification of ECM1 as the target gene.

From: ECM1 modified HF-MSCs targeting HSC attenuate liver cirrhosis by inhibiting the TGF-β/Smad signaling pathway

Fig. 2: DEG analysis and identification of ECM1 as the target gene.

A Volcano plot of DEGs in GSE103580. B Heat map of DEGs in GSE103580. G1 represents the cirrhotic group; G2 represents the noncirrhotic group. Red indicates upregulation; green represents downregulation. KEGG pathway analysis of upregulated DEGs (C) and downregulated DEGs (D). GO enrichment of upregulated DEGs (E) and downregulated DEGs (F). G Protein–protein interaction networks among the DEGs. H Expression of ECM1 in DEGs. I Western blotting analysis and semiquantitative analysis of ECM1 expression in the control group and the model group. Data are shown as the means ± SDs (*p < 0.05, **p < 0.01, ***p < 0.001).

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