Fig. 4: miR-578 expression was significantly decreased in IDD tissues.
From: Hsa_circ_0134111 promotes intervertebral disc degeneration via sponging miR-578
A miR-578 expression was lower in the IDD tissues compared to control tissues. B miR-578 expression was downregulated in the moderate/severe group compared to normal tissues or the mild group. C The expression of miR-578 was negatively correlated with circ_0134111 expression in the IDD samples. D IL-1β significantly decreased the miR-578 expression in NP cells. E The expression of miR-578 was downregulated in the NP cells after treatment with TNF-α. *p < 0.05, **p < 0.01, and ***p < 0.001.
