Table 2 Echocardiographic data.

From: Induction of apoptosis and autosis in cardiomyocytes by the combination of homocysteine and copper via NOX-mediated p62 expression

 

NR (n = 7)

HcyR (n = 7)

HcyR+NC (n = 7)

HcyR+Sip22phox (n = 6)

HcyR+Sip62 (n = 6)

Heart rate, beats/min

479 ± 44

485 ± 33

500 ± 26

487 ± 28

494 ± 22

LVEDD (mm)

5.56 ± 0.12

5.47 ± 0.43

5.56 ± 0.32

5.55 ± 0.26

5.50 ± 0.19

LVEF%

90.25 ± 2.14

89.36 ± 4.29

90.34 ± 2.01

90.23 ± 2.13

90.03 ± 2.46

E (mm/s)

326.70 ± 25.20

81.64 ± 71.88***

74.82 ± 81.05

266.50 ± 82.85 ##

303.40 ± 69.17§§§

A (mm/s)

115.80 ± 11.08

137.40 ± 16.61*

140.50 ± 15.27

153.30 ± 41.63

157.20 ± 42.83

E/A

2.85 ± 0.41

0.58 ± 0.0.46***

0.56 ± 0.67

1.93 ± 1.085##

2.03 ± 0.71§§§

E’ (mm/s)

49.43 ± 4.94

37.35 ± 4.47***

40.30 ± 6.01

48.34 ± 6.18#

49.74 ± 2.28§§

A′ (mm/s)

31.54 ± 3.69

105.70 ± 28.40 ***

102.0 ± 31.06

35.43 ± 8.16###

35.57 ± 8.29§§§

E′/A′

1.58 ± 0.23

0.40 ± 0.20***

0.47 ± 0.31

1.42 ± 0.53##

1.46 ± 0.35§§§

E/E′

6.65 ± 0.69

2.17 ± 1.89

1.89 ± 2.02

5.73 ± 1.51

6.07 ± 1.21

  1. Data are mean ± SD. n = no. of rats/group that were successfully evaluated by Doppler imaging.
  2. LVEDD LV end-diastolic diameter, LVEF left ventricular ejection fraction, E peak velocity of early mitral inflow, A peak velocity of late mitral inflow, E′ early diastolic velocity of the mitral annulus, A′ late diastolic mitral annulus velocity.
  3. *p < 0.05 vs. NR; ***p < 0.001 vs. NR; #p < 0.05 vs. HcyR+NC; ##p < 0.01 vs. HcyR+NC; ###p < 0.001 vs. HcyR+NC; §§p < 0.01 vs. HcyR+NC; §§§p < 0.001 vs. HcyR+NC. NR, HcyR+NC, HcyR+Sip22phox, HcyR+Sip62: see Table 1.
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