Fig. 6: Change of Erk1/2 signaling and autophagy-related protein levels by U0126 treatment. | Cell Death Discovery

Fig. 6: Change of Erk1/2 signaling and autophagy-related protein levels by U0126 treatment.

From: Targeting the Erk1/2 and autophagy signaling easily improved the neurobalst differentiation and cognitive function after young transient forebrain ischemia compared to old gerbils

Fig. 6

Western blot analysis of p-MEK1/2, MEK1/2, p-Erk1/2, Erk1/2, p-p90RSK and p-MSK1/2 in the hippocampus of the young gerbils treated with U0126 (A). Western blot analysis of Beclin-1, LC3-I and LC3-II in the hippocampus of the young gerbils treated with U0126 (B) (n = 7 per group; *p < 0.05, significantly different from the 14 days young group, #p < 0.05, significantly different from the young group at the same reperfusion time). Bars indicate mean ± SD.

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