Fig. 7: Change of Erk1/2 signaling and autophagy-related protein levels by 3MA treatment. | Cell Death Discovery

Fig. 7: Change of Erk1/2 signaling and autophagy-related protein levels by 3MA treatment.

From: Targeting the Erk1/2 and autophagy signaling easily improved the neurobalst differentiation and cognitive function after young transient forebrain ischemia compared to old gerbils

Fig. 7

Western blot analysis of Beclin-1, LC3-I, LC3-II, and Atg3 in the hippocampus of the young gerbils treated with 3MA (A). Western blot analysis of p-MEK1/2, MEK1/2, p-Erk1/2, Erk1/2, and p-p90RSK in the hippocampus of the young gerbils treated with 3MA (B) (n = 7 per group; *p < 0.05, significantly different from the 14-d young group, #p < 0.05, significantly different from the young group at the same reperfusion time). Bars indicate mean ± SD.

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