Fig. 6: Circ-DMNT1/p53 activates the JAK/STAT3 signaling pathway in trophoblast cells. | Cell Death Discovery

Fig. 6: Circ-DMNT1/p53 activates the JAK/STAT3 signaling pathway in trophoblast cells.

From: The possible involvement of circRNA DMNT1/p53/JAK/STAT in gestational diabetes mellitus and preeclampsia

Fig. 6

The expression of JAK2 and STAT3 protein were upregulated by the OE-circ or OE-p53, while were downregulated by the si-circ-1 or si-p53 in HTR-8/SVneo cells. **P < 0.001 compared with si-circ-NC or si-NC. ##P < 0.001 compared with OE-circ-NC or OE-NC. N = 3, repetition = 3.

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