Fig. 3: CRCSC-exos reduce anti-tumor immunity in CRC. | Cell Death Discovery

Fig. 3: CRCSC-exos reduce anti-tumor immunity in CRC.

From: Tumor stem cell-derived exosomal microRNA-17-5p inhibits anti-tumor immunity in colorectal cancer via targeting SPOP and overexpressing PD-L1

Fig. 3

A Representative images, volume, and weight of xenografts from mice after exosome treatment; B–E TNF-α, IL-2, IL-10, and TGF-β contents in mouse serum were determined using ELISA 72 h after exosome injection; F the histological characteristics of tumor tissues detected using HE staining; CD4 and CD8 expression in xenografts from mice detected using immunohistochemistry after exosome treatment. There were five mice in each group; *P < 0.05 vs the PBS group; the measurement data were expressed as mean ± standard deviation.

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