Table 1 Correlation of NOP expression with the clinicopathologic features of 288 patients with HCC.
Characteristics | Cases | NOP protein | P | |
|---|---|---|---|---|
Low expression | High expression | |||
Sex | ||||
Female | 36 | 13 | 23 | 1.000 |
Male | 252 | 95 | 157 | Â |
Age (years) | ||||
13–50 | 142 | 55 | 87 | 0.716 |
51–77 | 146 | 53 | 93 |  |
Hepatitis B surface antigen | ||||
Negative | 38 | 16 | 22 | 0.591 |
Positive | 250 | 92 | 158 | Â |
Child–Pugh classificationa | ||||
A | 284 | 107 | 177 | 1.000 |
B | 3 | 1 | 2 | Â |
Serum AFP (μg/L) | ||||
≤20 | 124 | 48 | 76 | 0.714 |
>20 | 164 | 60 | 104 | Â |
Microsatellite formation | ||||
No | 246 | 100 | 146 | 0.009 |
Yes | 42 | 8 | 34 | Â |
Tumor number | ||||
Single | 233 | 97 | 136 | 0.003 |
Multiple | 55 | 11 | 44 | Â |
Tumor size (cm) | ||||
≤5 | 147 | 64 | 83 | 0.038 |
>5 | 141 | 44 | 97 | Â |
Tumor encapsulation | ||||
No/incomplete | 216 | 89 | 127 | 0.025 |
Yes | 72 | 19 | 53 | Â |
Vascular invasion | ||||
No | 235 | 86 | 149 | 0.532 |
Yes | 53 | 22 | 31 | Â |
Liver cirrhosis | ||||
No | 75 | 31 | 44 | 0.488 |
Yes | 213 | 77 | 136 | Â |
Differentiation grade | ||||
I/II | 217 | 79 | 138 | 0.572 |
III/IV | 71 | 29 | 42 | Â |
TNM stage | ||||
I | 177 | 77 | 100 | 0.009 |
II/III | 111 | 31 | 80 | Â |
