Fig. 3: The expression of FAM84B significantly effected ESCC cell proliferation and cell cycle. | Cell Death Discovery

Fig. 3: The expression of FAM84B significantly effected ESCC cell proliferation and cell cycle.

From: Elevated FAM84B promotes cell proliferation via interacting with NPM1 in esophageal squamous cell carcinoma

Fig. 3

A Over-expression of FAM84B significantly increased the ability of proliferation in KYSE450. B Knock-down FAM84B dramatically decreased the ability of proliferation in KYSE150 and KYSE180 cells. C Over-expression of FAM84B significantly promoted the ability of colony formation in KYSE450. D Knock-down FAM84B inhibited the ability of colony formation in KYSE150 and KYSE180 cells. E Over-expression FAM84B promoted cell cycle by flow cytometry in KYSE450 cells. F Knock-down FAM84B inhibited cell cycle and arrests to the G1/S phase in KYSE150 and KYSE180 cells. G, H FAM84B knockdown markedly inhibited tumor growth and decreases the weight of the tumor mass in the xenograft system. Statistical analysis is performed with one-way ANOVA. *P < 0.05, ***P < 0.001.

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