Fig. 5: IRX5 overexpression inhibited glycolysis and promoted OxPhos.
From: IRX5 promotes adipogenesis of hMSCs by repressing glycolysis
A Principal component analysis (PCA) (n = 3). Two-dimensional clustergram depicts the internal structure of the metabolomics data set with respect to variance (n = 3). B Heatmap of significantly changed metabolites in glycolysis and OxPhos pathway analyzed by LC-MS/MS (n = 3). C Violin plot compared the metabolites intensities in glycolysis and OxPhos pathway (n = 3). D Glucose uptake assay valued the rate of glucose consumption (n = 8). E Lactate production assay determined the rate of lactate production (n = 8). Results are shown as mean ± SD. *p < 0.05, ** p < 0.01, *** p < 0.001, ****p < 0.0001.
