Fig. 1: IGF2BP3 was upregulated in EC and predicted poor overall survival. | Cell Death Discovery

Fig. 1: IGF2BP3 was upregulated in EC and predicted poor overall survival.

From: IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression

Fig. 1

A IGF2BP3 mRNA levels in EC obtained from TCGA dataset. B Kaplan–Meier analysis of overall survival in EC patients with high and low expression levels of IGF2BP3 from TCGA datasets. C The mRNA expression levels of IGF2BP3 in clinical EC tissues and normal endometrial tissues. D Representative images of IGF2BP3 protein expression in human endometrial tissues (left: normal endometrial tissue, right: EC tissue) (×200). E Mean IOD of IGF2BP3 after immunohistochemistry staining in human endometrial tissues. F Kaplan–Meier estimates of overall survival in 58 patients with EC according to the expression level of IGF2BP3 in IHC (patients were divided into low- and high-expression groups by the median of mean IOD, P = 0.03). *** P < 0.001. Data, mean ± S.D. All experiments were independently repeated with at least three replicates. Abbreviation: EC endometrial carcinoma, TCGA The Cancer Genome Atlas, UCEC Uterine corpus endometrial carcinoma, IOD Integrated optical density.

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