Fig. 4: Knockdown of LINC00958 offset the tumor-promoting role of IGF2BP3 in EC. | Cell Death Discovery

Fig. 4: Knockdown of LINC00958 offset the tumor-promoting role of IGF2BP3 in EC.

From: IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression

Fig. 4

A and B CCK-8 assays showed the proliferation of Ishikawa cells and HEC-1-A cells upon ectopic expression of IGF2BP3 combined with LINC00958-silenced expression. C EdU assays indicated the proliferation ability of Ishikawa cells stably transfected. D Migration and invasion assays showed invasion in Ishikawa cells stably transfected. On the right side of representative images are their quantification results. *P < 0.05, **P < 0.01, ***P < 0.001, “ns”, no statistical significance. Data, mean ± S.D. All experiments were independently repeated with at least three replicates.

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