Fig. 6: IGF2BP3 exerted its tumor-promoting effects via E2F3 in EC. | Cell Death Discovery

Fig. 6: IGF2BP3 exerted its tumor-promoting effects via E2F3 in EC.

From: IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression

Fig. 6

A and B CCK-8 assays showed the proliferation of Ishikawa cells and HEC-1-A cells overexpressing IGF2BP3 combined with E2F3-silenced expression. C EdU assays displayed the proliferation ability of Ishikawa cells overexpressing IGF2BP3 combined with E2F3-silenced expression. D Transwell assays indicated the migration and invasion of Ishikawa cells overexpressing IGF2BP3 combined with E2F3-silenced expression. On the right side of representative images are their quantification results. *P < 0.05, **P < 0.01, ***P < 0.001, “ns”, no statistical significance. Data, mean ± S.D. All experiments were independently repeated with at least three replicates.

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