Fig. 2: Differences between conventional and ceRNA mechanisms. | Cell Death Discovery

Fig. 2: Differences between conventional and ceRNA mechanisms.

From: The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer

Fig. 2

In conventional mechanism, RISCs induce mRNAs degradation through complete base pairing, while the translation of mRNAs is blocked by RISCs through incomplete base pairing. In ceRNA mechanism, lncRNAs sponge miRNAs by serving as ceRNAs to relieve mRNAs while further improve the abundance of expressed products. (By Figdraw (www.figdraw.com)).

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