Fig. 4: Mice with cardiac dysfunction were treated by inhibiting USP7.
From: Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1
a, b P5091 was intraperitoneally injected into mice for three consecutive days, and ultrasound Doppler was used to detect the EF% (ejection fraction) and FS% (fraction shortening) 3, 4, and 21 days after the operation. c, d sh-USP7 was injected into the myocardium of mice, and ultrasound Doppler was used to detect the EF and FS 3, 4, and 21 days after the operation. #Compared with the SHAM group, *Compared with the I/R group, P < 0.05, mean ± standard deviation (n = 3).
