Fig. 5: MiR-1277-5p is involved in the cross-talk between HOTAIR and ZEB1. | Cell Death Discovery

Fig. 5: MiR-1277-5p is involved in the cross-talk between HOTAIR and ZEB1.

From: HOTAIR/miR-1277-5p/ZEB1 axis mediates hypoxia-induced oxaliplatin resistance via regulating epithelial-mesenchymal transition in colorectal cancer

Fig. 5

A Veen diagram of candidate miRNAs. B Schematic illustration of the predicted miRNA (miR-1277-5p/miR-326) binding sites in HOTAIR and ZEB1 3'-UTR. C The relative expression level of miR-1277-5p after knocking down HOTAIR. D The relative expression level of ZEB1 after overexpressing miR-1277-5p or inhibiting miR-1277-5p. E The relative expression level of miR-1277-5p was confirmed after transfection of miR-1277 mimic, miR-1277-5p inhibitor, or corresponding negative control, respectively. ***p < 0.001, ###p < 0.001.

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