Fig. 1: circFTO is up regulated in ccRCC and correlated with worse prognosis.

A Heatmap of significant differential expressed circRNAs between tumor and normal tissue in ccRCC. B Scatterplots of differential expressed circRNAs between tumor and normal tissue. C Distribution of length of identified circRNAs. D Vocano plot of significant differential expressed circRNAs. E Genomic loci of FTO gene and circFTO. F Expression of circFTO in tumor and normal tissue identified by RNA in situ hybridization (ISH). G Prognostic significance of circFTO expression for ccRCC patients determined with ISH values. Median value was used as the cutoff.