Fig. 7: circFTO knockdown and mTOR inhibition suppressed the metastasis of ccRCC cells in vivo synergistically. | Cell Death Discovery

Fig. 7: circFTO knockdown and mTOR inhibition suppressed the metastasis of ccRCC cells in vivo synergistically.

From: Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma

Fig. 7

A and B H&E staining showed the metastasis of sh-NC/sh-circFTO transfected 786-O cells to mice lungs co-treated with negative control/Everolimus. C and D Bioluminescence imaging detected the metastasis ability of si-NC and si-circFTO luciferase (luc)-labeled 786-O cells to lungs co-treated with negative control/Everolimus. E Schematic diagram of circFTO/miR-514b-3p/DUSP4 in ccRCC.

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