Fig. 2: Ferr-1 inhibits ferroptosis in retinal tissues of DR rats. | Cell Death Discovery

Fig. 2: Ferr-1 inhibits ferroptosis in retinal tissues of DR rats.

From: Ferrostatin-1 alleviates tissue and cell damage in diabetic retinopathy by improving the antioxidant capacity of the Xc--GPX4 system

Fig. 2

A Perl’s staining detected iron deposition in retinal tissues. B Ferritin levels in retinal samples were detected by ELISA. C IHC detected GPX4 expression level in retinal tissues. D GSH/GSSG kit was used to detect the content and proportion of reduced/oxidized glutathione in tissues. ***P < 0.001 vs control. #P < 0.05, ##P < 0.01, ###P < 0.001 vs Model.

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