Fig. 2: Gut microbiome differences in PD mouse model.
From: Inflammatory gut as a pathologic and therapeutic target in Parkinson’s disease
A FISH analysis was used to distinguish the specific microbiota within the feces of the animals using probes for BAC303 (red), EREC482 (red), and LAB158 (red) with DAPI (blue). Immunofluorescent microscopy was used to collect the images of representative samples from each animal group (Scale bar = 50 um). B Differences in gut biome was measured for significance for each group by calculating probe fluorescence intensity/DAPI. ANOVA revealed significantly elevated BAC303 levels (****p < 0.0001), EREC482 levels (****p < 0.0001), and LAB158 levels (****p < 0.0001) in Tg control groups compared to both treatment groups and Wt animals (****p < 0.0001).
