Fig. 2: A549-Exos suppressed osteoclast differentiation and osseous resorption in vitro. | Cell Death Discovery

Fig. 2: A549-Exos suppressed osteoclast differentiation and osseous resorption in vitro.

From: Exosomal miR-328 originated from pulmonary adenocarcinoma cells enhances osteoclastogenesis via downregulating Nrp-2 expression

Fig. 2

A Fluorescence microscopy analysis of RAW 264.7 cells treated with DiO-labelled A549-Exos for 2 h. B TRAP staining images of mature osteoclasts processed with different concentrations of A549-Exos. Scale bar: 100 μm. C Quantitative assessment of the positive TRAP-stained osteoclasts in Fig. 2B (**P < 0.01). D–E Relative expression levels of Ctsk and TRAF-6 mRNA in Fig. 2B (**P < 0.01).

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