Fig. 7: TBK1 expression was increased in human diabetic retinas.
From: Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression
A Representative images of TBK1 immunostaining in human retinas. TBK1 was increased in retinal and choroidal vasculature with DR. B Statistical analysis of TBK1 expression in retinal superficial vessels in A. The data were means ± SD of three samples/group and assessed by student’s t-test. C Statistical analysis of TBK1 expression in choroidal vessels in A. The data were means ± SD of three samples/group and assessed by Welch’s t-test. D TBK1 expression in HRCECs was tested by western blot assay. Cells were treated with 30 mM glucose to establish a high glucose model. E Statistical analysis of the data shown in D. The data were means ± SD of three replicates/groups and assessed by student’s t-test. **P < 0.01.
