Fig. 3: MLKL is involved in RIPK3-mediated necroptosis after UVA irradiation. | Cell Death Discovery

Fig. 3: MLKL is involved in RIPK3-mediated necroptosis after UVA irradiation.

From: UVA induces retinal photoreceptor cell death via receptor interacting protein 3 kinase mediated necroptosis

Fig. 3

A–C Representative images and analysis of MLKL and PARP expression by Western Blot (n = 4–5 per group). D, E Representative images and analysis of TUNEL (green) and RIPK3 (red) expression by co-staining (Scale Bar: 20 μm) (n = 6 per group). F–H Representative images and analysis of Cleaved Caspase-8 and Cleaved Caspase-3 expression by Western Blot (n = 3 per group). Statistical significance was analyzed with the unpaired Student’s t-test. Statistical significance of compared with 0 J/cm2, 3.5 J/cm2, 7 J/cm2 is indicated as *, # and &. *P, #P or &P < 0.05, **P, ##P or &&P < 0.01, ***P, ###P or &&&P < 0.001, ****P, ####P or &&&&P < 0.0001. All values are expressed as mean ± SD.

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